Search Results

Study Published on Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves

October 9, 2015—Online in The New England Journal of Medicine (NEJM), Raj R. Makkar, MD, et al published a finding of reduced aortic valve leaflet motion seen on computed tomography (CT) in a patient who had a stroke after transcatheter aortic valve replacement (TAVR) during an ongoing clinical trial. This finding raised a concern about possible subclinical leaflet thrombosis and prompted further evaluation. The investigators advised that the condition resolved with therapeutic anticoagulation, but noted that the effect of this finding on clinical outcomes including stroke needs further investigation.

Five-Year PARTNER 2 Data Published Comparing TAVR Using Edwards Sapien XT Versus SAVR

February 27, 2020—The 5-year outcomes from the PARTNER 2 trial were published by Raj R. Makkar, MD, et al in The New England Journal of Medicine (NEJM; 2020;382:799–809).

MiRus Siegel 8-F TAVR System Evaluated in Early Feasibility Study

July 2, 2025—MiRus, LLC, announced the presentation of 30-day results from the United States early feasibility study (EFS) of the company’s Siegel transcatheter aortic valve replacement (TAVR) system.