Pulmonary Embolism Center

SPIRARE II Post Hoc Analyses Presented for Jupiter Endovascular’s Vertex Thrombectomy System

November 3, 2026—Jupiter Endovascular, Inc., announced findings from post hoc analyses of its SPIRARE II pivotal trial examining pulmonary artery (PA) pressure and right ventricular (RV) recovery after treatment with the company’s Vertex thrombectomy system for pulmonary embolism (PE).

The PERT Consortium Names Mark McIlduff as Executive Director

November 3, 2026—The PERT Consortium announced the appointment of Mark McIldiff as Executive Director.

Penumbra’s Lightning Flash 3.0 CAVT System Receives CE Mark Approval

November 2, 2026—Penumbra announced it has received CE Mark approval for the Lightning Flash 3.0 computer-assisted vacuum thrombectomy (CAVT) system, which includes significant upgrades to advance the company’s venous thromboembolism platform.

Inquis Medical Launches SENSE-PE Registry of Aventus Thrombectomy System

November 2, 2026—Inquis Medical announced the launch of SENSE-PE, a postmarket registry evaluating the safety and efficacy of the company’s Aventus thrombectomy system in patients with acute pulmonary embolism (PE).

SPIRARE II Results Published for Jupiter’s Vertex Thrombectomy System

October 20, 2026—Jupiter Endovascular, Inc. announced that the full results of the SPIRARE II pivotal trial, evaluating the company’s Vertex thrombectomy system in patients with acute, intermediate-risk pulmonary embolism (PE), were published in EuroIntervention by Sameh Sayfo, MD, et al.

HI-PEITHO Analysis Studies Predictors of Major Bleeding in Acute Intermediate-Risk PE

October 16, 2026—A post hoc analysis of the randomized HI-PEITHO study examined potential predictors of major bleeding in patients with acute intermediate-risk pulmonary embolism (PE) treated with ultrasound-facilitated catheter-directed thrombolysis (USCDT) using the Ekos endovascular system (Boston Scientific Corporation) plus anticoagulation (AC) or anticoagulation (AC) alone.

Thrombolex Device for Mechanically Channeled Thrombolysis Evaluated in RAPID-PE

October 13, 2026—Thrombolex, Inc., announced interim results from the first 150 patients enrolled in its RAPID-PE postmarket study, a prospective, multicenter, single-arm study evaluating on-the-table mechanically channeled thrombolysis using the Thrombolex device for acute intermediate-risk pulmonary embolism (PE).

FDA Clears E2 Hēlo Thrombectomy System and Integrated Blood Return System

October 13, 2026—Endovascular Engineering, Inc. (E2), a developer of technology for venous thromboembolism, announced FDA 510(k) clearance for both the Hēlo thrombectomy system and Hēlo Return, a blood return system.

Innova’s Laguna Thrombectomy System Evaluated in TRUST Pivotal Study for PE Indication

October 6, 2026—Innova Vascular, Inc. announced results from its pivotal TRUST study evaluating the treatment of pulmonary embolism (PE) with the company’s Laguna thrombectomy system.

STORM-PE and STRIKE-PE Data Presented for Penumbra’s CAVT for Pulmonary Embolism

October 6, 2026—Penumbra, Inc., announced new STORM-PE findings examining the relationship between activity recorded by wearable devices and clinic-based assessments of functional recovery after pulmonary embolism (PE).

Inquis Launches Aventus Thrombectomy Catheter With 360° Directional Aspiration for PE

September 30, 2026—Inquis Medical, a developer of treatments for venous thromboembolic disease, announced the United States commercial launch of the latest Aventus catheter, which received FDA 510(k) clearance in July 2026.

PRAGUE-26 Evaluates Interventional Strategy for PE in Intermediate-High–Risk Patients 

September 24, 2026—The PRAGUE-26 study, which is evaluating whether an interventional strategy can improve outcomes in patients with embolism, showed that catheter-directed thrombolysis (CDT) improved short-term clinical outcomes compared with standard anticoagulation therapy alone in patients with intermediate-high–risk pulmonary embolism (PE).

TRUST Pivotal Study of Innova’s Laguna Thrombectomy System Completes Enrollment

September 1, 2026—Innova Vascular, Inc. announced the completion of patient enrollment in the TRUST pivotal investigational device exemption clinical study, which is evaluating the safety and effectiveness of the company’s Laguna thrombectomy system for the treatment of pulmonary embolism (PE).

The PERT Consortium CEO Michelle Lanno to Step Down at Year’s End

July 20, 2026—Michelle Lanno, Chief Executive Officer of The PERT Consortium, announced she will be stepping down from her role effective December 31, concluding more than a decade of leadership that began with the organization’s founding in 2015.

SYMPHONY-PE Analysis Shows Early Thrombectomy Linked to Better Outcomes

June 19, 2026—Imperative Care announced findings from a post hoc analysis of the SYMPHONY-PE trial that suggest that mechanical thrombectomy performed within 12 hours of diagnosis may be associated with greater hemodynamic and right ventricular recovery in patients with intermediate-risk pulmonary embolism (PE) compared with treatment performed later.

ENGULF Analysis Shows Reduced Blood Loss With E2’s Hēlo System in PE Procedures

May 4, 2026—A comparative analysis from the ENGULF trial demonstrated that using blood return during continuous aspiration thrombectomy dramatically reduced blood loss by 97%, while maintaining hemodynamic efficacy and improving procedural efficiency.